Diarrhea weight loss You could feel the want to attempt everything to lose weight, especially if you’ve tried multiple diets in a row without seeing the desired results or if you’ve experienced the now-famous yo-yo effect. High-dose laxatives are one of the less common treatments that some people are drawn to in order to achieve this goal. But be smart about it: Will diarrhea cause me to lose weight? Am I going to drop a lot of fat? Is there no risk?